正德十六年,武宗驾崩,朱厚熜即位,建元嘉靖。李言闻被封为太医院吏目。 李言闻好友吴药师因治错小郡主的病,被关入牢中。吴药师临终托孤,将女儿吴斯语许配给李时珍。 长大后李时珍进阳明书院学习,和荆王府世子朱成翊成为同学。朱成翊希望拉拢李时珍为自己所用,却被李时珍严词拒绝。朱成翊遂与李时珍成了死对头。 李时珍偶遇一个美丽的少女朱苌葶,却发现她脉象异常,命不久已。李时珍给她治疗多年顽症,两人产生爱慕之情。一次偶然的机会,李时珍发现少女居然是荆王府郡主。 李时珍希望能考取功名,得个一官半职,与苌葶也不是不可能。朱成翊得知李时珍赶考,便派人买通主考官。 李时珍被考官诬陷舞弊,赶出考场。李时珍心结郁积,一病不起。 苌葶暗中派人送信与李时珍商量私奔,得不到任何回应,失望之余病情加重,也卧倒不起。荆王急忙下令要李言闻替女儿看诊,可是李时珍命在旦夕,李言闻根本无法离开。危急时刻,斯语出面坦承自己的药膳是治疗郡主的关键,立下生死状,进入荆王府救治苌葶。 成翊要求斯语留在自己身边,在王府享受荣华富贵,被斯语拒绝。 李时珍终于和斯语完婚,并且跟随父亲正式开始行医。 李时珍经过几轮考试,终于进入太医院。 此时朱苌葶拜道士陶仲文为师,整日沉迷于炼丹食丹不能自拔;而蓝行义则和已成为杨妃的杨雪英勾结,利用所学医术,在后宫兴风作浪;朱成翊也来到京城,和严世蕃勾结一气,贪淫无道;景王和裕王争夺太子之位,严嵩和徐阶两派政治斗争激烈。李时珍卷入这波澜诡谲阴谋重重的宫廷斗争之中…… 李时珍发现苌葶体内有铅中毒的迹象,于是劝解苌葶暂停服丹,苌葶不听,两人发生激烈争执。 李时珍向嘉靖进言,请求皇上别再服食丹药,嘉靖大怒,驳回他重修本草的提议。嘉靖吃了苌葶进献的长生不老丹药,忽然病重晕倒。严嵩父子趁机把责任推到李时珍身上,将其下狱。 郡主查出其实始作俑者是朱成翊和严世蕃采办回来的假鹿茸。严世蕃将朱成翊推到前面成为替罪羊。嘉靖将朱成翊斩首,荆王痛失爱子。 李时珍终于进入太医院禁地查找武宗之死的真正原因,他发现武宗之死竟是一个巨大的阴谋,而且与嘉靖有关……李时珍为华南洗冤昭雪的想法成为泡影。 郡主积毒已久,终于身亡。李时珍心灰意冷,萌生去意。他将全部精力投入到修本草上,希望从此人们能辨别真伪,世间不再有假药害人。 李时珍回到蕲州,风餐露宿,亲身试药,为修本草收集第一手资料。 当年的倭寇小藤以商人身份来找李时珍拜师学医。李时珍见其诚恳,收留了他。小藤发现《本草纲目》书稿,顿生贼心。他趁李时珍不备,偷走书稿。斯语阻止小藤,虽保住了书稿,但不幸被杀害。李时珍悲痛欲绝。 万历十四年前后,《本草纲目》编写完成,王世贞答应为该书写序。万历接到王世贞的上疏,下令让李时珍进京献书。可正当李时珍准备动身之际,蕲州附近开始流行“天花”,李时珍决定暂不进京,赶赴疫区为百姓治病。剧照图册2(11张) 在李时珍等人的努力下,“天花”得到控制。可李时珍自己却因过度劳累病倒了。临终时,李时珍嘱咐建元将《本草纲目》进奉于朝,福泽天下后世。在幻觉中,李时珍仿佛看到《本草纲目》被进奉给皇上的情景。 三年后,李建元将《本草纲目》进献给神宗。 神宗派使者将《本草纲目》送往日本、朝鲜等地,使我中华文明福泽世界。
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